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How to identify arousals? PLM?
#21
RE: How to identify arousals? PLM?
I was just taking a peek through uptodate files I have and I think they sum it up well, to paraphrase.

PLM accompanies many sleep and neurologic disorders and increases in frequency with age. PLM does not have a consistent relationship with symptoms or with polysomnograph findings such as arousals. PLM is generally considered to be an age related phenomenon, a response to arousals, or related to other disorders. Occasionally PLM occurs abundantly and causes frequent arousals in the absence of other disorders in which case the PLM may be the primary cause of symptoms.

This all falls in lines with my earlier comments that all this is extremely complicated and the hard part is trying to determine cause of your symptoms. Your apnea appears treated so does not appear to be the cause of symptoms. You appear to have PLM but it is unclear if it is a cause of symptoms or just something you have. A titration study is about the only way you can try to confirm breathing is good and PLM is or isn't an issue although it is still an imperfect test. Treatment if PLM is found or believed to be an issue is to trial different medications, supplements, diet modifications etc to see if they help. Main medications appear to be ropinirole, gabapentin, pregabalin and occasionally clonazepam. All of these can help or make your symptoms worse or introduce other symptoms, same as supplements etc. Unfortunately there isn't a good way to measure success so all you can do is try different options and see if something makes you feel better.

What I have found in my journey through my own issues and sleep research is that the only thing doctors are halfways decent at treating is sleep apnea. Most of these other sleep issues are extremely complicated and they don't have great tests or treatments for them.
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#22
RE: How to identify arousals? PLM?
Thank you all for the reactions. Much appreciated! I'll be talking to my sleep doc within 2 months. In the mean time I'll give several options a try. When I come across some new insights I'll be happy to post it here.
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#23
RE: How to identify arousals? PLM?
The past few months I've been trying dietary changes along with some homeopathic remedies. Didn't help at all unfortunately. 

My sleepdoc (pulmonologist) told me that PLMD sometimes exacerbates as a result of xpap treatment. That's why they treat apnea first and take care of PLMD afterwards. He gave me a referral to a neurologist, who I will be seeing tomorrow.

Just wondering. Does any of you experience waking up early in the morning? I have this all the time and wake up between 06.00-06.15 am, no matter how late I go to sleep (usually around 23.00).
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#24
RE: How to identify arousals? PLM?
(09-11-2022, 03:20 AM)permabear Wrote: Just wondering. Does any of you experience waking up early in the morning?

Yes.  I generally go to bed around 23:00 and wake up at 04:30 almost every day lately!  Strangely, I feel refreshed but I doubt 5.5 hours of sleep is enough for me.  I can usually get back to sleep in a few minutes.

I have not been able to narrow down anything in particular.  OSCAR data usually shows nothing around the time I first wake up.  No need for a bathroom break. No other family members awake at that hour.  Pets are all fast asleep.  Only thing I can think of is something external, maybe my neighbor lets his dog out, or a loud car drives down the street?? Huh
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#25
RE: How to identify arousals? PLM?
I just received the results of a new sleeptest, done with CPAP. Results were as follows:
PLM index: 84/h
PLM arousal index: 4/h
AHI/RDI: 0.0/h

My neurologist considered the PLM index to be quite high. But since most of the movements apparently don't coincide with an arousal, this should be nothing to worry about he said. Furthermore my sleep architecture looked normal, with a fair amount of REM and deep sleep.

I'd love to hear your comments on this conclusion. How reliable is the arousal index? Is it the outcome of a manual scoring process (leaving room for false negatives?). I forgot to ask doc so I hope you can help me with this.

I did the sleeptest because I still experience fatigue after more than a year of CPAP treatment. Both AHI and FL seem to be treated effectively so I wanted to rule out the possibility of PLM disrupting a good night's rest.

Of course there could be other culprits in play. I'm just deciding what possibilities I should be exploring at this point.
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