6 hours ago
RE: Medical Evidence of High Res Data...a physician perspective
Hi - I'm not a doctor ... BUT I've been in the trenches for 20 months with apnea versus vert. artery occlusion, and doctors who can't be bothered to look at detailed data OR research. I'm also a cybersecurity guy who spent the last 10 years diagnosing bad things happening to really complicated systems so I've been debugging my medical issues.
In addition to this board, which has been a life-saver -possibly, quite literally- I have gotten a lot of mileage from an AI app called Perplexity (perplexity.ai) - it has a PRO mode that I subscribe to which you can direct to only search vetted quality research and professional sites such as NIH, Heart assoc, JAMA, Frontiers in ..., and so forth. I am a cybergeek with experience in AI going back to the '80s and I approve of this app.
For example, I queried Perplexity about apnea and ischemic stroke (my vert. artery) and it returned this reference as it constructed its reply
from American College of Cardiology
With this explanation:
2. Hypoperfusion During Sleep
OSA can worsen hypoperfusion in patients with vertebral artery occlusion by disrupting normal cerebral hemodynamics. The repeated apneic episodes cause fluctuations in blood pressure and oxygen levels, which can lead to reduced cerebral perfusion, especially during sleep when systemic blood pressure is naturally lower. This is particularly concerning in patients with vertebral artery occlusion, where collateral circulation may already be insufficient to maintain adequate perfusion
. Studies using transcranial Doppler have demonstrated that OSA can cause a "cerebral blood flow steal" phenomenon, where blood is diverted away from ischemic areas, worsening hypoperfusion
Of course, sanity checking is still required. Verify, then trust.
--
Hope this helps - I have found it an incredibly useful tool in helping me advocate for treatment --- which I am still not receiving, by the way.
Thanks for stepping up for your patients!
In addition to this board, which has been a life-saver -possibly, quite literally- I have gotten a lot of mileage from an AI app called Perplexity (perplexity.ai) - it has a PRO mode that I subscribe to which you can direct to only search vetted quality research and professional sites such as NIH, Heart assoc, JAMA, Frontiers in ..., and so forth. I am a cybergeek with experience in AI going back to the '80s and I approve of this app.
For example, I queried Perplexity about apnea and ischemic stroke (my vert. artery) and it returned this reference as it constructed its reply
from American College of Cardiology
With this explanation:
2. Hypoperfusion During Sleep
OSA can worsen hypoperfusion in patients with vertebral artery occlusion by disrupting normal cerebral hemodynamics. The repeated apneic episodes cause fluctuations in blood pressure and oxygen levels, which can lead to reduced cerebral perfusion, especially during sleep when systemic blood pressure is naturally lower. This is particularly concerning in patients with vertebral artery occlusion, where collateral circulation may already be insufficient to maintain adequate perfusion
. Studies using transcranial Doppler have demonstrated that OSA can cause a "cerebral blood flow steal" phenomenon, where blood is diverted away from ischemic areas, worsening hypoperfusion
Of course, sanity checking is still required. Verify, then trust.
--
Hope this helps - I have found it an incredibly useful tool in helping me advocate for treatment --- which I am still not receiving, by the way.
Thanks for stepping up for your patients!
