G'day Dave. Welcome to Apnea Board.
Could I ask you to reformat and upload your chart again, please? We need to get rid of the calendar and pie chart which are covering up important information. We also need to see the following graphs (only): Event flags, Flow rate, Pressure (not mask pressure), Leak rate, Flow limitations, and (if it will fit) Snore. The instructions for organising the charts are linked in my signature.
The second thing to do is find that sleep study report. It's important to know if all those central apneas were pre-existing, or have only come along since you started treatment.
In the interim, I'd think about raising the minimum pressure to about 8.0, to overcome the obstructive apneas. At the same time, reduce EPR to 1 or (if you can tolerate it) turn EPR off altogether. This should have the effect of re-balancing your blood gases. CPAP makes your breathing more efficient (and EPR even more so), and the level of CO2 in your blood remains artificially low. The brain sees the low CO2, says "I don't need to breathe just now" and you get a central apnea. (Well that's the layman's version coz I can't spell hypocapnia
)
It's possible that the late centrals are sleep-wake junk, as you transition out of sleep and go into a dozing phase with irregular breathing. So let's have a closer look - can you zoom in onto a two minute window during that heavy apnea period?
These suggestions are somewhat of a guess, but won't do any harm and may well help. Let's see the full data and we can be more definitive.