Treatment-Emergent Central Apnea

Treatment-Emergent Central Apnea occurs when a person that has no to minimal Central Apnea starts using a CPAP/APAP/BiLevel device and sees a marked increase in Central Apnea.

Causes

1. Initial use of a CPAP/APAP/BiLevel Device
2. Increase in Pressure Support (PS) or EPR (Expiratory Pressure Relief)/Flex on a CPAP/APAP/BiLevel Device
3. Increase in pressure on a CPAP/APAP/BiLevel Device
4. Anything that increases the efficiency of your breathing

Description

A Primary driver for breathing is a high level of pCO2 in the arterial blood that is sensed by Chemoreceptors. This is sensed and a signal to breathe is initiated. It is not a low level of oxygen that provides a signal to breathe, it is a high level of CO2. How does this occur? Our CPAP/APAP/BiLevel Devices are designed to improve our breathing. One part of this is to improve the exchange of blood gasses. When too much CO2 is washed out no signal to breathe is delivered, thus a Treatment-Emergent Central Apnea. Keep in mind that we are dealing with people who have been suffering from poor breathing for years. Their bodies have adjusted to this environment, they are used to higher levels of CO2 in their blood so lowering the CO2 to more 'normal' levels passes through a threshold that fails to produce a breathe now signal.

Treatment

1. Continued use of a CPAP/APAP/BiLevel Device. Treatment-Emergent Central Apnea often goes away as your body adjusts to treatment. This takes 2-3 months of adaption
2. Decrease in Pressure Support (PS) or EPR (Expiratory Pressure Relief)/Flex on a CPAP/APAP/BiLevel Device
3. Decrease in pressure on a CPAP/APAP/BiLevel Device
4. Anything that decreases the efficiency of your breathing
5. EERS (Enhanced Expiratory Rebreathing Space) The theory is that the use of positive air pressure, especially with pressure support (PS) or exhale pressure relief (EPR) can result in a drop in carbon dioxide in the blood, which through various respiratory feedback mechanisms can result in the emergence of central apnea (CA). By adding dead-spece or a larger volume EERS does the via a mask modification which slightly increases the amount of CO2 that is rebreathed. This effectively eliminated the central apnea. Note that this is a process that your medical team has not likely heard of and because it requires a mask modification is frowned on by many in the medical profession. I'll add that this process is used extensively by a few doctors in cooperation with a few DMEs and Sleep Centers.

Definitions

Hypocapnia or hypocapnea (from the Greek words υπό meaning below normal and καπνός kapnós meaning smoke), also known as hypocarbia, sometimes incorrectly called acapnia, is a state of reduced carbon dioxide in the blood. Hypocapnia usually results from deep or rapid breathing, known as hyperventilation.

references

Treatment of positive airway pressure treatment-associated respiratory instability with enhanced expiratory rebreathing space (EERS).

Alternative approaches to treatment of Central Sleep Apnea

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