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{{OSCARcleanup}}'''<span class="new-win">[https://translate.google.com/translate?hl=af&sl=en&tl=af&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide Afrikaans] / [https://translate.google.com/translate?hl=ar&sl=en&tl=ar&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide في الصفحة] / [https://translate.google.com/translate?hl=bg&sl=en&tl=bg&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide български] / [https://translate.google.com/translate?hl=zh_CN&sl=en&tl=zh_CN&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide 中国] /[https://translate.google.com/translate?hl=zh_TW&sl=en&tl=zh_TW&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide 臺灣] /[https://translate.google.com/translate?hl=da&sl=en&tl=da&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide Dansk] / [https://translate.google.com/translate?hl=de&sl=en&tl=de&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide Deutsch] / [https://translate.google.com/translate?hl=el&sl=en&tl=el&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide Ελληνικά] / [https://translate.google.com/translate?hl=es&sl=en&tl=es&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide Español] / [https://translate.google.com/translate?hl=fr&sl=en&tl=fr&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide Français] / [https://translate.google.com/translate?hl=he&sl=en&tl=he&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide עברית] / [https://translate.google.com/translate?hl=hu&sl=en&tl=hu&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide Magyar] / [https://translate.google.com/translate?hl=it&sl=en&tl=it&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide Italiano] / [https://translate.google.com/translate?hl=ko&sl=en&tl=ko&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide 한국어] / [https://translate.google.com/translate?hl=nl&sl=en&tl=nl&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide Nederlands] / [https://translate.google.com/translate?hl=no&sl=en&tl=no&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide Norsk] / [https://translate.google.com/translate?hl=pl&sl=en&tl=pl&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide Polskie] / [https://translate.google.com/translate?hl=pt&sl=en&tl=pt&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide Português] / [https://translate.google.com/translate?hl=ro&sl=en&tl=ro&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide Românește] / [https://translate.google.com/translate?hl=ru&sl=en&tl=ru&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide Russkiy] / [https://translate.google.com/translate?hl=fi&sl=en&tl=fi&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide Suomalainen] / [https://translate.google.com/translate?hl=sv&sl=en&tl=sv&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide Svenska] / [https://translate.google.com/translate?hl=th&sl=en&tl=th&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide ภาษาไทย] / [https://translate.google.com/translate?hl=tl&sl=en&tl=tl&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide Pilipino] / [https://translate.google.com/translate?hl=tr&sl=en&tl=tr&u=https://www.apneaboard.com/wiki/index.php/OSCAR_-_The_Guide Türkçe] </span>'''<br /> --> Do not use these buttons when you are on a translated page. Just close this tab to go back. <-- <br />
==<big><big>'''OSCARObstructive sleep apnea (OSA)''' - the or '''O'''pen '''S'''ource '''C'''PAP '''A'''nalysis '''R'''eporter</big></big>=='''OSCARobstructive sleep apnea syndrome''' is software that the most common type of sleep apnea and is caused by obstruction of the upper airway. It is compatible with Windowscharacterized by repetitive pauses in [[breathing]] during [[sleep]], Macdespite the effort to breathe, and Linux operating systemsis usually associated with a reduction in [[blood oxygen saturation]]. These pauses in breathing, developed for reviewing and exploring data produced by supported CPAP, bilevelcalled [[apnea]]s (literally, ventilators"without breath"), and related machines used in the treatment of sleep apnea. Oscar requires that data is collected on an SD card which MUST be inserted into the PAP machine during use typically last 10 to record detailed data40 seconds. <br />
==Common features The individual with OSA is rarely aware of detailed graphs==having difficulty breathing, even upon awakening. It is recognized as a problem by others witnessing the individual during episodes or is suspected because of its effects on the body. OSA is commonly accompanied with [[snoring]].
[[File:OSCAR daily screen.png|thumb|none|1000px|Oscar daily screenSymptom]] <br />----=== Left side-bar ==={||[[File:OSCAR Side-bar.png|thumb|none]1000px|Left side bar]]|The left part of the Daily screen is referred to as the ''left side-bar''. It contains details of your machine and its settingss may be present for years, your AHI and other sleep indicatorseven decades without identification, and the amount of during which time you were asleep.<br />Starting from the top, sufferer may become conditioned to the key parts of the left side-bar are# Program identification, menu, [[daytime sleepiness]] and tabs, as found on all screens within OSCAR# The current date. Click the small green arrows to move back & forth by one day. Click the Green arrow & bar >| to move to the latest date fatigue associated with data. Click the small black triangle to make the calendar appear or disappear.# Tabs to select details, events, notes, and bookmarks. These will be discussed in greater detail below.# AHI Summary. This is your '''apnea / hypopnea index''' for the sessions under review. It is the total number of apneas and hypopneas divided by the total hours significant levels of [[sleepdisturbance]]. Generally, this will be for the whole night, however, if you have turned any sessions on or off (See No 11 below) then the AHI is given only for the sessions turned on.# Machine type and settings summary. This gives the make and model of the CPAP machine. The PAP mode is the particular algorithm set on the machine (many machines can operate in more than one mode). It also shows the pressure settings. If you hover the mouse cursor over the machine name, the model number and serial number will appear in Persons who sleep alone without a poplong-up box. '''Note:''' The settings for PC, S, and S/T modes on Philips Respironics System One machines term human partner may be displayed as random garbage numbers - this is a known problem and will be fixed in a later release of Oscar.# Session starting, ending, and total times. Shows when the machine was turned on and off, and the total elapsed time. Note that although this is used to calculate the time asleep, the CPAP machine has no way of knowing if you were actually asleep or not.# Event rates per hour. A simplified view of the different types of events you have experienced. Note that some machines display more or fewer event types, and these can be selected in the Event flag selector on the Daily page.# Statistics for pressure, leaks, snores, and respiration. Detailed information told about your respiration throughout the night. The statistics panel gives details of your pressures, minute ventilation, respiration rate, and other important parameters. For each parameter (referred to as a 'channel') the panel shows the minimum recorded, the median, 95th percentile and the maximum. Also shown are the total time in apnea, and the time over the leak redline. For Resmed machines, this is 24 L/min. For all machines the redline number can be set in the menu File | Preferences | CPAP. # Machine Settings Details. A more complete set of machine settings giving you the pressure and other settings for your machine. The settings shown will vary according to the type of machine.# Session Information. Each time the machine is started then stopped is called a session. If you their [[sleep right through the night, that is a single session. If you stop the machine for a toilet break then start it again, then two sessions will be recorded.# Buttons (bars) to turn sessions on and off. Clicking on these buttons will include or exclude sessions from the display of the night's data. Clicking on the blue and yellow session buttons will include or exclude sessions from the display of the night's data. This can be useful if (for example) you had a very brief nap in the afternoon and want to exclude it from the night's results. Note that turning a session off will change the calculated AHI for the night. Note also that sessions can be turned on and off using the small green/black buttons in the section information panel. When a session is off the button changes to black / reddisorder]] symptoms.
|}Since the muscle tone of the body ordinarily relaxes during sleep, and since, at the level of the throat, the human airway is composed of walls of soft tissue, which can collapse, it is easy to understand how breathing can be obstructed during sleep. Although a very minor degree of OSA is considered to be within the bounds of normal sleep, and many individuals experience episodes of OSA at some point in life, a much smaller percentage of people are afflicted with chronic, severe OSA.
----==== The Calendar ===={||[[File:OSCAR CalendarMany people experience episodes of OSA for only a short period of time.png|thumb|left]250px|Calendar]]|The calendar This can be useful for navigationthe result of an upper respiratory infection that causes nasal congestion, but if you are posting an OSCAR Daily Detail graph on along with swelling of the forumthroat, it should be minimizedor tonsillitis that temporarily produces very enlarged tonsils. To minimize the monthly calendarThe Epstein-Barr virus, for example, just click on the triangle is known to be able to dramatically increase the left size of lymphoid tissue during acute infection, and OSA is fairly common in acute cases of severe infectious mononucleosis. Temporary spells of OSA syndrome may also occur in individuals who are under the current dateinfluence of a drug (such as alcohol) that may relax their body tone excessively and interfere with normal arousal from sleep mechanisms.
If you click on a date in the calendar, the daily data for that date loads into the daily data window. It's also important to understand that the data for any particular date is the data for the NIGHT that started on on that date and ended the following morning. And that's true regardless of whether you get to bed before midnight.
Now, look at Here are the little arrows AHI levels of severity for Sleep Apnea in the calendar. Adults:<br />
# The two arrows that surround the bubble with the highlighted date move one day backward or forward. # The third outside arrow on the far right ->| will immediately jump to the last date with data.# The two arrows on the blue bar with the month's name allow you to jump forward or backward by a month.# Pressing the downward triangle between the month and the year allows you to quickly change to a different month. # Clicking the year allows you to quickly change to a different year.# Pressing the upward-facing arrow in the bubble with the date in it will hide the calendar and change that triangle to a downward-facing triangle. Clicking the downward-facing triangle will show the calendar. The calendar covers up a lot of useful information and should always be hidden when making screenshots for uploading to a forum.|}Mild: 5----====Pie Chart===={||[[File:OSCAR Pie chart.png|thumb|left]250px|Pie chart]]14<br/>|You can see a pie chart depicting the breakdown of your events.
<!-- Deleted the next paragraph when V1.1.0 is releasedTo turn the pie chart on and off, go to the File menu and select '''File | Preferences | Appearance'''. For posting charts to the forum it's best to turn the pie chart '''off''' as it covers up more valuable information.-Moderate 15->29<!-- To be inserted when V1.1.0 is released.--br />To turn the pie chart on and off, press '''Ctrl-P''' on your keyboard (For macOS press '''fn-F3'''). Alternatively, use the menu item '''View | Show Pie Chart'''. For posting charts to the forum it's best to turn the pie chart '''off''' as it covers up more valuable information.
|}Severe: 30+<br />
<!-- Delete this graphic whgen V1.1.0 is released
[[File:OSCAR Preferences Appearance.PNG | 800 px]]
-->
----
====Summary Information (AHI, Machine, Hours, Event rates)====
Items 4, 5, 6, and 7 in the sidebar image are collectively the summary information. They show your apnea-hypopnea index (AHI), brief details of your machine and its settings, the time you slept, and the events which occurred during your sleep.
Note that the AHI shown is only for the 'sessions' which are turned on (see below). The summary of events will only show those which are turned on in the event flag selector. The available events will vary among different types of machines.
<br><br>
----
==== Tabs: Details, events, notes and bookmarks ====
{| class="wikitable"
|- style="vertical-align:top;"
|[[File:OSCAR Events tab.PNG|thumb|left]250px|Tabs]]
|
* The '''Details tab''' is the default view which shows the statistics, machine settings, etc.
* The '''Events tab''' Shows every apnea, hypopnea, large leak, and other significant events during the night. The numbers in brackets are the duration of the event in seconds. Clicking on any event will zoom the chart to show that event in detail.
* The '''Notes tab''' allows you to keep a daily journal of your sleep experience. There are basic formatting buttons available as well as a slider to register how you feel (on a scale of Zombie to Awesome). You can also enter your weight each day.
** The notes for a particular day can be included in the printed report. It's necessary to deselect all graphs except one, using the chart selector menu at the bottom right of the page. To print the report, go to the menu '''File | Print Report'''. Notes you have saved will be included in the printout.
** You can export all your notes as an XML file for backup purposes or additional analysis. Use the menu option '''File | Backup Journal'''.
** Oscar will calculate your '''body mass index (BMI)''' at the bottom of the Notes section. You must enter your weight each day. You must also enter your height in your profile (see [http://www.apneaboard.com/wiki/index.php?title=Running_OSCAR_for_the_first_time Running Oscar for the First Time] ). If either the weight or height is not entered the BMI calculation will not appear.
* The '''Bookmarks tab''' lets you record the time of significant events you may wish to refer back to, such as an exceptionally long apnea.
----
====Creating a bookmark====
Bookmarks are created using the [[http://www.apneaboard.com/wiki/index.php?title=OSCAR_Organization_-_Daily_Page#Tabs:_Details.2C_events.2C_notes_and_bookmarks bookmark tab]] on the daily page:
# Click on the tab to open bookmarks
# On the flow rate graph, place the cursor on the event you wish to record (eg an apnea)
# Click the Add Bookmark button. A bookmark stating the time and date will be created.
[[FileHere are the AHI levels of severity for Sleep Apnea in Children:OSCAR create bookmark.png]]<br />
You can add text to a bookmarkMild:# Select the bookmark # Double1-click the words "Bookmark at xx:xx:xx" in the Notes column# Type in your text# Press Enter.----=====Reviewing bookmarks=====In the [[http:5 Adenotonsillectomy evaluation<br //www.apneaboard.com/wiki/index.php?title=OSCAR_Organization_-_Basic_Parts_of_the_OSCAR_Window#The_Right_Side_Bar right sidebar]] click on the Bookmarks button at the bottom of the sidebar. The sidebar will show a list of all the bookmarks which have been created. To go to a particular bookmark, click on the date. OSCAR will open the daily page at that particular date. You can then click on a bookmark and OSCAR will adjust the display to show the event which has been selected. You can search for particular text in your bookmarks using the search window at the top of the sidebar (under the word Bookmarks).----=====Deleting bookmarks=====On the Daily page, select the bookmark you wish to delete, then click "Remove Bookmark" at the bottom of the panel. >
Moderate 5-10<!--See also [[http:br //www.apneaboard.com/wiki/index.php?title=Bookmarks&action=edit&redlink=1 Bookmarks]] -->|}----=== The daily detailed graphs ===The main part of the daily page is given over to the detailed graphs. These allow you to inspect all the important things which happened during the night, right down to a breath-by-breath review.----====Common features of detailed graphs====Each daily graph chart has a number of features in common:
* '''Turn graphs on or offSevere:''' You can turn individual graphs on and off using the chart selector at the bottom right corner of the chart area. Click on the selector and a small menu will pop up, listing all the available graphs. Click on any one to turn it on or off. When turned on, the item will show a small green & black icon. If turned off, it will show a red and black icon. The available graphs will depend on your machine, and on settings in the preferences dialog.* '''Zoom level:''' The default view shows the whole night's chart compressed onto a single panel. You can zoom in and out for a closer view as follows: # Left click anywhere on a graph; # Right click anywhere to zoom out; # Place the cursor on a graph, hold the Ctrl button and rotate the scroll wheel;# Use the keyboard Up Arrow to zoom in and the Down Arrow to zoom out; # To zoom out to the full view you can also right-click on any graph title and select "100% zoom level". Alternatively press and hold the Escape (Esc) key or Down Arrow on your keyboard for a couple of seconds. * '''Time scale:''' Along the bottom of each graph is a time scale to show when events occurred.* '''Pin chart in position:''' Double-click on the title of a graph to pin it in position. Once pinned, the graph will appear at the top of the screen and will not scroll with the other graphs.* '''Resize chart:''' You can change the vertical height of any graph by clicking in the divider line and dragging it up or down.* '''Pop out chart:''' Right-click on the graph label and select "Popout graph". A copy of the graph will be created in its own window, which can then be placed anywhere on the screen. If you pop out more than one graph, they will share a common window.* '''Clone graph:''' Right-click on the graph label and select "Clone graph". A copy of the graph will be created below the original. The cloned graph can be zoomed independently of all other graphs. To remove the clone, right-click on the title and select "Remove clone".* '''Reset graph layout:''' If you have changed the vertical height of one or more graphs, double click on a graph title and select "Reset graph layout". All graphs will be restored to their normal height.* '''Y Axis:''' If you want to change the vertical scale of a graph, right-click in the label of a graph and select "Y axis". A small pop-up will show, and give the options Autofit, Defaults, and Override. Select override, the adjust the minimum and maximum numbers until the trace on the graph is to your liking. Note that you must keep the mouse cursor within the pop-up - if it strays outside, the pop-up will disappear.<br>[[File:OSCAR Graph Y10-axis scaling.png | 600 px]]30<br/>* '''CPAP overlays:''' Oscar can include a marker for each of the events on any of the graphs. Right-click the graph title and select 'CPAP Overlays'. A pop-up will appear, allowing you to turn on or off each type of event. The events will appear as a short tick along the top of the graph.* '''Oximeter overlays:''' If you have a pulse oximeter synched to Oscar you can display certain parameters using the oximeter overlay option.* '''Dotted lines:''' Oscar will display dotted lines across a graph to aid in reading it. The available lines will vary depending on the particular graph. Right-click on a graph title and select "Dotted lines". A pop-up will appear, with a list of available lines which you can turn on or off.
----==Daily (Standard Charts)==To reset the graph order for the Standard Charts click on '''''View/Reset Graphs/Standard'''''<br>These are the charts that are most used to see how your therapy is doing. When submitting for review these charts should be provided in a full night view. If you wish to submit a partial night highlighting a problem feel free to do so in addition to the full night.*3-Minute view to see the form of the breaths*10-15 minute view to evaluate breathing patterns such as CSR and PP/Periodic BreathingExtremely Severe: 30+
== Signs and symptoms ==
----
===Event Flags===
Common signs of OSA include unexplained daytime sleepiness, restless sleep, and loud snoring (with periods of silence followed by gasps). Less common symptoms are morning headaches; [[insomnia]]; trouble concentrating; mood changes such as irritability, anxiety and depression; forgetfulness; increased heart rate and/or blood pressure; decreased sex drive; unexplained weight gain; increased urination and/or [File:OSCAR event flags.PNG[nocturia]]; frequent heartburn or gastroesophageal reflux disease; and heavy night sweats.
The Event Flags graph normally appears at the top of the stack. It shows each event (Obstructive Apnea ('''Adults''OA'''''), Central Apnea/Clear Airway ('''''CA'''''), Hypopnea ('''''H'''''), Large Leak ('''''LL'''''), etc.) as a vertical bar. You can select which events to display using the event flag selector at the bottom left of the chart area. The available flags will vary depending on your machine. The graphical display of events is useful in determining whether they occurred at a particular time, in clusters, or spaced throughout the night.
Each event type In adults, the most typical individual with OSA syndrome suffers from obesity, with particular heaviness at the face and neck. Obesity is not always present with OSA; in the Event Flags graph fact, a significant number of adults with normal body mass indices (BMIs) have decrease in muscle tone causing airway collapse and sleep apnea. The cause of this decreased tone is not presently understood. The hallmark symptom of OSA syndrome in adults is excessive daytime sleepiness. Typically, an adult or adolescent with severe long-standing OSA will have a corresponding entry fall asleep for very brief periods in the sidebar summary areacourse of usual daytime activities if given any opportunity to sit or rest. This behavior may be quite dramatic, sometimes occurring during conversations with others at social gatherings.
[[File:OSCAR sidebar summaryThe hypoxia (absence of oxygen supply) related to OSA may cause changes in the neurons of the hippocampus and the right frontal cortex. Research using neuro-imaging revealed evidence of hippocampal atrophy in people suffering from OSA. They found that some sufferers have problems in mentally manipulating non-verbal information and in executive function.png]]
First, Events only show if you have had them at some point, OSCAR remembers. If you have NEVER had a Clear Airway/Central Apnea event ('''Children''CA''''') recorded, none will show. The same for RERAs ('''''RE'''''), though not all machines report RERAs. Second, if you have previously had an event type such as Clear Airway/Central Apnea event ('''''CA''''') recorded, that category will always display even if you have none on the current night.The events shown here are all, alright, almost all, reported by your xPAP machine.
The exception: In Although this so called "[[hypersomnolence]]" (excessive sleepiness) may also occur in children, it is not at all typical of young children with sleep apnea. Toddlers and young children with severe OSA instead ordinarily behave as if "over-tired" or "hyperactive." Adults and children with very severe OSA also differ in typical body habitus. Adults are generally heavy, with particularly short and heavy necks. Young children, on the '''''File/Preferences/CPAP''''' tab there other hand, are generally not only thin, but may have "failure to thrive", where growth is a section reduced. Poor growth occurs for those two reasons: the work of you breathing is intense enough that calories are burned at high rates even at rest, and the nose and throat are so obstructed that eating is both tasteless and physically uncomfortable. OSA in children, unlike adults, is often caused by obstructive tonsils and adenoids and may want to experiment called '''''Custom CPAP User Event Flagging'''''sometimes be cured with tonsillectomy and adenoidectomy. This allows you to define different Flow Restrictions and Event Durations
This problem can also be caused by excessive weight in children. In this case, the symptoms are more like the symptoms adults feel: restlessness, exhaustion, etc.
[[File:OSCAR Custom CPAP Event FlaggingChildren with OSA may experience learning and memory deficits and OSA has also been linked to lowered childhood IQ scores.png|500px]]----====Issue - Positional Apnea====
Positional Apnea is caused by misalignment of the airway typically tucking the chin down.<br />It is normally detected by '''clusters of Obstructive and Hypopnea events''' usually associated with an uneven and smaller/narrower Flow Rate chart.== Risk factors ==
[[File:Severe Positional Apnea.png|500px]]
see Old age is often accompanied by muscular and neurological loss of muscle tone of the Wiki article [[Optimizing_therapy#Positional_Apnea]]-upper airway. Decreased muscle tone is also temporarily caused by chemical depressants; alcoholic drinks and sedative medications being the most common. Permanent premature muscular tonal loss in the upper airway may be precipitated by traumatic brain injury, neuromuscular disorders, or poor adherence to chemical and or speech---====Issue - Other====Correlation with other charts indicating cause and effecttherapy treatments.
----===Flow Rate===ResMed S9Individuals with decreased muscle tone, Philips Respironics System Oneincreased soft tissue around the airway, and Fisher & Paykel Icon machines record Flow Rate data if structural features that give rise to a narrowed airway are at high risk for OSA. Men, in which the card anatomy is typified by increased mass in the CPAP machine during torso and neck, are at increased risk of developing sleep apnea, especially through middle age and later. Women suffer typically less frequently and to a lesser degree than do men, owing partially to physiology, but possibly also to differential levels of progesterone. Prevalence in post-menopausal women approaches that of men in the nightsame age range.<br>The DeVilbiss IntelliPAP does NOT record Flow Rate dataWomen are at greater risk for developing OSA during pregnancy.
[[File:OSCAR flow rate graphOSA also appears to have a genetic component; those with a family history of it are more likely to develop it themselves. Lifestyle factors such as smoking may also increase the chances of developing OSA as the chemical irritants in smoke tend to inflame the soft tissue of the upper airway and promote fluid retention, both of which can result in narrowing of the upper airway. An individual may also experience or exacerbate OSA with the consumption of alcohol, sedatives, or any other medication that increases sleepiness as most of these drugs are also muscle relaxants.png]]
This graph is probably the most used in analyzing and interpreting CPAP data. It shows airflow in and out of your lungs throughout the night. The flow above the zero line is inhalation and below the line is exhalation. The events are shown on this graph as well as on the event flags graph. You can zoom in to examine an event more closely. == Epidemiology ==
Placing the cursor on any event will create a small pop-up detailing the type and duration of the event in seconds.
OSA is more frequent than [[File:OSCAR flow rate detail.pngcentral sleep apnea]]and is the most common category of sleep-disordered breathing. It is a common condition in many parts of the world.
Nearly all that is happening throughout the night can be seen in the Flow Rate graph though usually If studied carefully in a zoomed view. Tidal Volumes and Minute Vent can be seen via the 'volume under the curve', flow limits may show as sleep lab by [[polysomnography]] (formal "grassysleep study" on the full night view but are readily apparent when viewed with the breath waveform ), it is readily distinguished, typically 2-3 minutesbelieved by some authorities that approximately 1 in 5 American adults would have at least mild OSA. Leaks may sometimes be distinguished by a difference The precise prevalence of OSA among the adult population in volume between inhale western Europe and exhaleNorth America, however, has not been confidently established. Periodic Breathing can In the mid-1990s it was estimated to be confirmed easily on this chart and serious breathing patterns such as CSR can be identified 3-4% of women and Flow Limits become readily apparent.----====Issue 6- Positional Apnea (Chin tucking)====[[File:Severe Positional Apnea FL Closeup7% of men.png|800px]]----====Issue - Arousal/Recovery Breathing====[[File:RERA 2.png|800px]]
[[File:RERA 1.png|800px]]== Causes ==
additional examples are in the above sections<br />'''Common causes'''
Most cases of OSA are believed to be caused by:
* old age (natural or premature),
* brain injury (temporary or permanent),
* decreased muscle tone,
* increased soft tissue around the airway (sometimes due to obesity), and
* structural features that give rise to a narrowed airway.
* [[Issue Decreased muscle tone can be caused by drugs or alcohol, or it can be caused by neurological problems or other disorders. Some people have more than one of these issues. There is also a theory that long- Positional Apnea (Chin tucking)]]term snoring might induce local nerve lesions in the pharynx in the same way as long----====Issue - Periodic Breathing (CSRterm exposure to vibration might cause nerve lesions in other parts of the body. Snoring is a vibration of the soft tissues of the upper airways, PB)====Note: ResMed (incorrectly) labels all periodic breathing as CSR.All Periodic Breathing should be viewed and studies have shown electrophysiological findings in a zoomed view to identify its propertiesthe nerves and muscles of the pharynx indicating local nerve lesions.
'''Craniofacial syndromes'''
Philips Respironics machines flag breathing There are patterns of unusual facial features that meets their definition occur in recognizable syndromes. Some of ''periodic breathing'' (PB)these craniofacial syndromes are genetic, others are from unknown causes. On the Philips Respironics web pagesIn many craniofacial syndromes, PB is defined as "Periodic breathing is defined as alternating periods of hyperventilation with waxing/waning tidal volume..." Typically the waxing and waning pattern must be quite regular in visual appearance and it must present for at least a minute or two for PB to be scored. PB is flagged with a green background on features that are unusual involve the flow rate data. Oftennose, but not alwaysmouth and jaw, there will be CAs (or Hs or sometimes OAs) scored at the nadir of the cycle. Sometimes the System One will only flag the most obvious part of the cycle: <br />[[File:PB_zpsee6cff1e.png]]<br />A bit of PB now and then is nothing to worry about. However, there is one form of PB that is called Cheyne-Stokes Respiration (CSR) that is clearly associated with some forms of heart diseaseresting muscle tone, including congestive heart failure. CSR is very regular and has a CA put the individual at the nadir of the cycle (although the CA may be mis-scored as an OA or a UA). If you have serious heart disease and you see a lot of PB scored in your flow rate data, it is worth mentioning it to your cardiologist as well as your sleep doctorrisk for OSA syndrome.
''Detecting Periodic Breathing on other CPAPs''Down Syndrome is one such syndrome. In this chromosomal abnormality, several features combine to make the presence of obstructive sleep apnea more likely. The specific features in Down Syndrome that predispose to obstructive sleep apnea include: relatively low muscle tone, narrow nasopharynx, and large tongue. Obesity and enlarged tonsils and adenoids, conditions that occur commonly in the western population, are much more likely to be obstructive in a person with these features than without them. Obstructive sleep apnea does occur even more frequently in people with Down Syndrome than in the general population. A little over 50% of all people with Down Syndrome suffer from obstructive sleep apnea, and some physicians advocate routine testing of this group.
Once you know what PB looks likeIn other craniofacial syndromes, you can often spot suspicious patterns by simply scrolling through the Flow Rate data in a 5-10 minute windowabnormal feature may actually improve the airway, but its correction may put the person at risk for obstructive sleep apnea after surgery, when it is modified. Cleft palate syndromes are such an example. Any periodic waxing/waning patterns will show up at that magnitudeDuring the newborn period, all humans are obligate nasal breathers. Whether this The palate is worth doing on a regular basis both the roof of the mouth and the floor of the nose. Having an open palate may make feeding difficult, but generally does not interfere with breathing, in fact - if the nose is another question altogethervery obstructed an open palate may relieve breathing. Unless you have There are a co-morbid condition that number of clefting syndromes in which the open palate is associated with PB (such as congestive heart failure)not the only abnormal feature, PB additionally there is a narrow nasal passage - which may not something you need to spend much time worrying about be obvious. In such individuals, closure of the cleft palate- whether by surgery or trying to locate in your databy a temporary oral appliance, can cause the onset of obstruction.
Here's Skeletal advancement in an example effort to physically increase the pharyngeal airspace is often an option for craniofacial patients with upper airway obstruction and small lower jaws (mandibles). These syndromes include Treacher Collins Syndrome and Pierre Robin Sequence. Mandibular advancement surgery is often just one of PB that the modifications needed to improve the airway, others may be CSR pulled from a ResMed machine:<br />include reduction of the tongue, tonsillectomy or modified [[File:CSR-example_zpsee76d5af.jpguvulopalatoplasty]]<br />----=====Cheyne Stokes Respiration Description (CSR)====='''CSR breathing'''.
'''Post-operative complication'''
OSA is a also serious post-operative complication that seems to be most frequently associated with pharyngeal flap surgery, compared to other procedures for treatment of velopharyngeal inadequacy (VPI). In OSA, recurrent interruptions of respiration during sleep are associated with temporary airway obstruction. Following pharyngeal flap surgery, depending on size and position, the flap itself may have an "obturator" or obstructive effect within the pharynx during sleep, blocking ports of airflow and hindering effective respiration. There have been documented instances of severe airway obstruction, and reports of post-operative OSA continue to increase as healthcare professionals (i.e. physicians, speech language pathologists) become more educated about this possible dangerous condition. Subsequently, in clinical practice, concerns of OSA have matched or exceeded interest in speech outcomes following pharyngeal flap surgery.
'''Evaluation  '''https://wwwThe surgical treatment for velopalatal insufficiency may cause obstructive sleep apnea syndrome. When velopalatal insufficiency is present, air leaks into the nasopharynx even when the soft palate should close off the nose. A simple test for this condition can be made by placing a tiny mirror at the nose, and asking the subject to say "P". This p sound, a plosive, is normally produced with the nasal airway closed off - all air comes out of the pursed lips, none from the nose. If it is impossible to say the sound without fogging a nasal mirror, there is an air leak - reasonable evidence of poor palatal closure.ncbiSpeech is often unclear due to inability to pronounce certain sounds.nlmOne of the surgical treatments for velopalatal insufficiency involves tailoring the tissue from the back of the throat and using it to purposefully cause partial obstruction of the opening of the nasopharynx.nihThis may actually cause OSA syndrome in susceptible individuals, particularly in the days following surgery, when swelling occurs (see below: Special Situation: Anesthesia and Surgery).gov/books/NBK448165<br />
Cheyne-Stokes respiration is characterized by alternating apnea and hyperventilation during sleep, mostly in the N1 and N2 sleep, and also when awake. This can be clinically observed and documented with a cyclic variation of breathing pattern with a change in saturation from 90% to 100%. Minute ventilation is not routinely monitored during sleep studies. The hyperventilation is documented by rising and falling chest excursions and the tidal volume. If the patient is on a ventilator, then the cyclical change in tidal volume and minute ventilation can be graphed together. '''The apnea/hyperapnea cycle is around 45 minutes to 75 minutes.'''. This cycle is longer than other causes of central sleep apnea cycle, which ''' typically have a cycle length of 30 to 45 minutes'''. Cheyne-Stokes respiration is worse in the supine position or moving from supine to lateral body position.<br /><br />== Pathophysiology ==
The normal [[sleep cycle|sleep/wake cycle]] in adults is divided into [[REM]] (rapid eye movement) sleep, [[non-REM]] (NREM) sleep, and consciousness. NREM sleep is further divided into Stages 1, 2 and 3 NREM sleep. The deepest stage (stage 3 of NREM) is required for the physically restorative effects of sleep, and in pre-adolescents this is the period of release of human growth hormone. NREM stage 2 and REM, which combined are 70% of an average person's total sleep time, are more associated with mental recovery and maintenance. During REM sleep in particular, muscle tone of the throat and neck, as well as the vast majority of all skeletal muscles, is almost completely attenuated, allowing the tongue and soft palate/oropharynx to relax, and in the case of sleep apnea, to impede the flow of air to a degree ranging from light snoring to complete collapse. In the cases where airflow is reduced to a degree where blood oxygen levels fall, or the physical exertion to breathe is too great, neurological mechanisms trigger a sudden interruption of sleep, called a neurological arousal. These arousals rarely result in complete awakening, but can have a significant negative effect on the restorative quality of sleep. In significant cases of OSA, one consequence is sleep deprivation due to the repetitive disruption and recovery of sleep activity. This sleep interruption in stage 3 (also called [[slow-wave sleep]]), and in REM sleep, can interfere with normal growth patterns, healing, and immune response, especially in children and young adults.
'''Etiology '''https://www.ncbi.nlm.nih.gov/books/NBK448165<br />Cheyne-Stokes respiration is a specific form of periodic breathing (''' waxing and waning amplitude of flow or tidal volume''') characterized by a '''crescendo-decrescendo pattern of respiration between central apneas or central hypopneas.''' The American Academy of Sleep Medicine (AASM) recommends to score a respiratory event as Cheyne-Stokes breathing if both of the following criteria are met:[/size][/color]== Diagnosis ==
# ''' There are episodes of at least three consecutive central apneas and/or central hypopneas separated by a crescendo and decrescendo change in breathing amplitude with a cycle length of at least 40 seconds (typically 45 to 90 seconds).'''
# ''' There are five or more central apneas and/or central hypopneas per hour associated with the crescendo/decrescendo breathing pattern recorded over a minimum of two hours of monitoring.'''<br />
<br />
Diagnosis of OSA is often based on a combination of patient history and tests (lab- or home-based). These tests range, in decreasing order of cost, complexity and tethering of the patient (number and type of channels of data recorded), from lab-attended full polysomnography ("sleep study") down to single-channel home recording. In the USA, these categories are associated with insurance classification from Type I down to Type IV. Reimbursement rules vary among European countries.
So, waxing and waning pattern with a central event between them and duration per the above.----'''Polysomnography'''
====Issue - PLM (Periodic Leg Movement====Polysomnography in diagnosing OSA characterizes the pauses in breathing. As in central apnea, pauses are followed by a relative decrease in [[File:RLS 10Min.png|800pxblood oxygen]]----====Issue - Various (Flow Limitation, Snoring, Mouth Breathing)=========Classes of inspiratory flow shapes=====and an increase in the [[File:Flowlimitations Classes.pngblood carbon dioxide]]. Whereas in central sleep apnea the body's motions of breathing stop, in OSA the chest not only continues to make the movements of inhalation, but the movements typically become even more pronounced. Monitors for airflow at the nose and mouth demonstrate that efforts to breathe are not only present, but that they are often exaggerated. The chest muscles and diaphragm contract and the entire body may thrash and struggle.
====Additional Info - Flow Limitation/UARS and BiPAP====Wiki article on An "event" can be either an [[Flow Limitation/UARS and BiPAPapnea]], is authored characterized by complete cessation of airflow for at least 10 seconds, or a well-known MD, who deals extensively with [[hypopnea]] in which airflow decreases by 50 percent for 10 seconds or decreases by 30 percent if there is an associated decrease in the oxygen saturation or an arousal from sleep. To grade the severity of sleep disordersapnea, and the number of events per hour is reported as the [[AHI|apnea-hypopnea index]] (AHI). An AHI of less than 5 is considered an Expert on UARSnormal.Article Subtitles:* UARS: A Critical Link to Optimizing PAP Therapy Results* UARS as MiniAn AHI of 5-Suffocations* UARS 15 is not Mutually Exclusive of Hypopneas or Apneas* UARS Assessment and Treatment mild; 15-30 is Critical to Titration Success* “Consensus Medicine” Covered up The Science of UARS* What’s in a Name?* Start Connecting Some Zzzzzots* Can You Feel '''Anxiety''' in your Sleep?* Is '''Bilevel''' the Answer?* UARS Diagnosis moderate and Medicare* Summing UpBrief Summary:<br />for all practical purposes, the following three terms are interchangeable:# UARS (upper airway resistance)# Flow limitation# RERAs (respiratory effort-related arousal)more than 30 events per hour characterizes severe sleep apnea.
Monitor your RDI vs your AHI. RDI = apneas + hypopneas + RERAs/Flow Limitation/UARS.<br />BiLevel for MOST with a diagnosis of UARS<br /> Quoting the article ''"in our clinical and research experience, we are using gaps of 'Home oximetry''4 to 12 cm of water''' in our patients. My personal bilevel settings are 21/12.5 for a gap of 8.5.
In our prescriptions for bilevelpatients who are at high likelihood of having OSA, I would venture a randomized controlled trial found that the '''average gap is in the 5 home [[oximetry]] (a non-invasive method of monitoring blood oxygenation) may be adequate and easier to 6''' range with tremendous variation, including some with obtain than formal polysomnography. High probability patients were identified by an [[Epworth Sleepiness Scale (ESS)]] score of 10 or greater and a '''gap [[Sleep apnea clinical score (SACS)]] of only 2 15 or 3'''greater. Those with a lower gap requirement would likely do as well on FLEX or APAPHome oximetry, but to repeathowever, the large majority of our patients have a gap of 4 does not measure [[apneic event]]s or greaterrespiratory event-related arousals and thus does not produce an AHI value."''<br />
This calls for a BiLevel.== Treatment ==
----
===Pressure===There are a variety of treatments for OSA; use is determined by an individual patient's medical history, the severity of the disorder and, most importantly, the specific cause of the obstruction.
A 'common' complaint is that In acute infectious mononucleosis, for example, although the airway may be severely obstructed in the first 2 weeks of the illness, the presence of lymphoid tissue (suddenly enlarged tonsils and adenoids) blocking the 'pressure' throat is so high that it blows too hardusually only temporary. That is not pressure, that A course of anti-inflammatory steroids such as prednisone (or another kind of glucocorticoid drug) is flow. All xPAP devices attempt often given to maintain constant pressurereduce this lymphoid tissue. When a 'leak' occursAlthough the effects of the steroids are short term, in most affected individuals, the pressure delivered tonsillar and adenoidal enlargement are also short term, and will be reduced on its own by the blower moves more air to compensate time a brief course of steroids is completed. In unusual cases where the enlarged lymphoid tissue persists after resolution of the acute stage of the Epstein-Barr infection, or in which medical treatment with anti-inflammatory steroids does not adequately relieve breathing, tonsillectomy and maintain pressureadenoidectomy may be urgently required.
Try thisOSA in children is sometimes due to chronically enlarged tonsils and adenoids. Tonsillectomy and adenoidectomy is curative. The operation may be far from trivial, especially in the worst apnea cases, in which growth is retarded and abnormalities of the right heart may have developed. Even in these extreme cases, the surgery tends to cure not only the apnea and upper airway obstruction, but allows normal subsequent growth and development. Once the high end-expiratory pressures are relieved, the cardiovascular complications reverse themselves. The postoperative period in these children requires special precautions (see "Surgery and obstructive sleep apnea syndrome" below).<br />
# Start your xPAP The treatment of OSA in adults with your mask offpoor oropharyngeal airways secondary to heavy upper body type is varied.# Now hold your breathUnfortunately, and close your eyes so the air doesn't blow in them while you# Place your mask on (hand holding is OK). The 'blowing' stops immediately after you put this most common type of OSA, unlike some of the mask on as the blower speed returns to normal. You ca also do this by using your hand to seal cases discussed above, reliable cures are not the maskrule.
Some treatments involve lifestyle changes, such as avoiding alcohol and medications that relax the central nervous system (for example, sedatives and muscle relaxants), losing weight, and quitting smoking. Some people are helped by special pillows or devices that keep them from sleeping on their backs, or oral appliances to keep the airway open during sleep. For those cases where these conservative methods are inadequate, doctors can recommend continuous positive airway pressure (CPAP), in which a face mask is attached to a tube and a machine that blows pressurized air into the mask and through the airway to keep it open. There are also surgical procedures intended to remove and tighten tissue and widen the airway, but none has been reproducibly successful. Some individuals may need a combination of therapies to successfully treat their condition.
====Practical Demonstration of Pressure====It's simple#Take a tall glass of water and a straw#Place the straw down to near the bottom of the glass, now let your youth loose and pretend you are a kid and blow bubbles.<br /><br /><br /><br />How did it feel? Any issues? Didn't think so.<br /><br /><br /><br />'Physical intervention'''
What just happened?* You exerted enough force to displace the water and blow bubbles. * This force, assuming 8 inches of water, The most widely used current therapeutic intervention is equal to the maximum positive airway pressure produced by whereby a CPAP, 20 cm breathing machine pumps a controlled stream of water (cmw). A BiLevelair through a mask worn over the nose, the next class of device upmouth, it is 10 inches of water or 25 cmwboth. Most therapy is around 4 inches The additional pressure splints or 10 cmwholds open the relaxed muscles, just as air in a balloon inflates it.<br /><br />There are several variants:
Many xPAP user complain about :: (CPAP), or continuous positive airway pressure, in which a computer controlled air flow generator, generates an air stream at a constant pressure. This pressure is prescribed by the patient's physician, based on an overnight test or titration. Newer CPAP models are available which slightly reduce pressure upon exhalation to increase patient comfort and compliance. CPAP is the most common treatment for obstructive sleep apnea.:: (BPAP), or [[bilevel positive airway pressure]], also known as [[variable positive airway pressure]] (VPAP) or BiPAP, uses an electronic circuit to monitor the "high" patient's breathing, and provides two different pressures involved, a higher one during [[inhalation]] and a lower pressure during [[exhalation]]. This system is just more expensive, and is sometimes used with patients who have other coexisting respiratory problems and/or who find breathing out against an increased pressure to be uncomfortable or disruptive to their sleep.:: (APAP), or [[automatic positive airway pressure]], is the newest form of such treatment. An APAP machine incorporates pressure sensors and a practical demonstration of computer which continuously monitors the pressures involved in xPAP therapypatient's breathing performance. It does not mean that you do not have issues related adjusts pressure continuously, increasing it when the user is attempting to breathe but cannot, and decreasing it when the pressureis higher than necessary. Although FDA approved, these devices are still considered experimental by some.
====Pressure and Mask Pressure====A second type of physical intervention, a [[Mandibular advancement splint]] (MAS), is sometimes prescribed for mild or moderate sleep apnea sufferers. The pressure graph shows device is a mouth guard similar to those used in sports to protect the pressure as teeth. For apnea patients, it varies over timeis designed to hold the lower jaw slightly down and forward relative to the natural, relaxed position. The mask pressure graph shows This position holds the tongue farther away from the pressure at back of the mask on a breath-by-breath basisairway, and may be enough to relieve apnea or improve breathing for some patients.
[[File:OSCAR pressure.pngOral appliance]]therapy is less effective than CPAP, but is more 'user friendly'. Side-effects are common, but rarely is the patient aware of them.
Zooming in shows how the mask pressure is a high-resolution chart sampled 25 times per second, while the pressure is only sampled once per second. Depending on your machine settings there may be several traces shown - usually the inhale pressure (IPAP) and exhale pressure (EPAP). '''Pharmaceuticals'''
[[File:OSCAR pressure detailThere are no effective drug-based treatments for obstructive sleep apnea that have FDA approval. However, a clinical trial of mirtazapine, has shown early promise at the University of Illinois at Chicago. This small, early study found a 50% decrease in occurrence of apnea episodes and 28% decrease in sleep disruptions in 100% of patients (twelve patients) taking them. Nonetheless, due to the risk of weight gain and sedation (two risk factors and consequences of sleep apnea) it is not recommended. An effort to improve the effects of mirtazapine by combining it with another existing medication was canceled during Phase IIa trials in 2006. Dr. David Carley and Dr. Miodrag Radulovacki, the sleep researchers who were behind the initial clinical trial of mirtazapine are now working on a new treatment that consists of two other existing medications taken off-label together for treatment of sleep apnea.png]]
----Other serotonin effecting agents that have been explored unsuccessfully as a treatment for apnea include fluoxetine, tryptophan and protriptyline.
===Flow Limit.===Philips Respironics: PR machines do not produce this chart, instead they show FL events on Oral administration of the Events chart.<br><br>ResMed: Flow Limits are calculated as an index, 0-1, indicating methylxanthine theophylline (chemically similar to caffeine) can reduce the flatness number of the breath-form on the flow rate chart. Zero means noneepisodes of apnea, severity increasing but can also produce side effects such as the index approaches oneheart palpitations and [[insomnia]]. These show as a varying height vertical barTheophylline is generally ineffective in adults with OSA, but is sometimes used to treat central sleep apnea (see below), and infants and children with apnea.
This is an important chart. Flow Limits When other treatments do not completely treat the OSA, drugs are the sometimes prescribed to treat a patient'foundation' of obstructive events. The least severe of these events are flow limits followed by hypopnea and then obstructive apneas daytime sleepiness or [[somnolence]]. They are often identified These range from stimulants such as a fundamental part of RERAs and UARSamphetamines to modern anti-narcoleptic medicines. <br>Note that on this chart flow limits are underThe anti-reported as compared to what we can visualize on the flow rate graph discussed abovenarcoleptic medicine modafinil is seeing increased use.
If you have a lot In most cases, weight loss will reduce the number and severity of flow limits hereapnea episodes. In the morbidly obese, it is a good idea to review major loss of weight (such as what occurs after bariatric surgery) can sometimes cure the Flow Rate chart for Flow Limits that do not show in this chartcondition.
[[File:OSCAR flow limitation.png]]'''Neurostimulation'''
====Issue Some researchers believe that OSA is at root a neurological condition, in which nerves that control the tongue and soft palate fail to sufficiently stimulate those muscles, leading to over- Pressure Increasing===='''Flow Limits are often relaxation and airway blockage. A few experiments and trial studies have explored the main driver use of pressure increases'''pacemakers and similar devices, especially with ResMed devices. Seeing Flow Limits in this graph is almost always accompanied by an increase in pressure as programmed to detect breathing effort and deliver gentle electrical stimulation to the ResMed algorithms depend heavily on muscles of the flow limits that are shown in this graphtongue.
====ResMed - AUTOMATED CONTROL FOR DETECTION OF FLOW LIMITATION - Patent Application====[https://wwwThis is not a common mode of treatment for OSA patients, but it is an active field of research.freepatentsonline.com/y2011/0203588.html AUTOMATED CONTROL FOR DETECTION OF FLOW LIMITATION]
Highlights'''Surgical intervention'''
A known algorithm that number of different surgeries are available to improve the size or tone of a patient's airway. For decades, [[tracheostomy]] was the only effective treatment for sleep apnea. It is used today only in rare, intractable cases that have withstood other attempts at treatment. Modern operations employ one or more of several options, tailored to automatically set each patient pressure in APAP machines is called ResMed AutoSet's needs. All Success rates are directly proportional to the accuracy in all, the AutoSet device, and its algorithm, is excellent for treating OSA patientsinitial diagnosis of the site of obstruction.
The ResMed AutoSet algorithm responds :: ''Nasal surgery'', including [[turbinectomy]] (removal or reduction of a nasal turbinate), or straightening of the nasal septum, in patients with nasal obstruction or congestion which reduces airway pressure and complicates OSA.:: ''Tonsillectomy and/or adenoidectomy'' in an attempt to increase the size of the airway.:: ''Removal or reduction of parts of the soft palate'' and some or all of the [[uvula]], such as [[uvulopalatopharyngoplasty]] (UPPP) or laser-assisted uvulopalatoplasty (LAUP). Modern variants of this procedure sometimes use radiofrequency waves to three thingsheat and remove tissue.:: ''Reduction of the tongue base'', either with laser excision or radiofrequency ablation.:: ''Genioglossus Advancement'', in which a small portion of the lower jaw that attaches to the tongue is moved forward, to pull the tongue away from the back of the airway.# flow limitation:: ''Hyoid Suspension'', in which the hyoid bone in the neck, another attachment point for tongue muscles, is pulled forward in front of the larynx.# snore :: ''Maxillomandibular advancement (audible noiseMMA) ''. MMA is the most effective sleep apnea surgical procedure currently available, with reduction of the AHI to less than 15 in over 90% of patients, and # apnoeareduction of AHI to <5 in ~45% of patients. MMA was once thought to be fairly invasive, but has shown to be less painful, in general, than a UPPP soft palate procedure. The associated surgical risks are low, including bleeding, infection, malocclusion, and permanent numbness of the chin and lip. In general, patient perceptions of surgical outcome have been very favorable.
The ResMed AutoSet algorithm monitors patient flow and raises pressure when it detects flow limitation or snore. Because apnoeas are normally preceded by periods role of surgery in the treatment of sleep apnea has been questioned repeatedly as the long term success rate of flow limitation (also called partial obstruction) or snoring, apnoeas are rarely encounteredthe procedures has come into question. As a backup measurePatient selection in the past was oftentimes quite poor, pressure is also raised if an apnoea is detectedresulting in poor overall results. In Potential surgical candidates should now be extensively examined to assure the absence site of any measured flow disturbance, the pressure obstruction is allowed clearly evident prior to decay slowly and hopefully an equilibrium pressure will be achieved that allows the patient to sleep arousal-freeany surgical intervention. The AutoSet algorithm responds proportionally patient's age, weight and so other factors may make them a metric is used bad candidate for each condition to which surgery. When a patient can tolerate it responds, positive air pressure treatment is the gold standard. The metrics used are: However, surgical intervention is a flattening index viable option for flow-limitationthose patients who cannot, a calibrated RMS measure of sound averaged over an inspiration for snore and the length of any apnoea detectedor refuse, to utilize CPAP.
A '''flattening indexCompression stockings''' is a non-dimensional feature (e.g., a real number) calculated using a patient's inspiration waveform. It attempts to measure essentially how flat-topped the waveform is. A feature of flow limitation is that while the downstream pressure is sufficiently low to keep the tube collapsed the flow-rate will be more or less maintained at a constant value, regardless of changes to the driving pressure. In a patient with flow-limited breathing this equates to an inspiratory waveform with a flat top (i.e., a constant inspiratory flow-rate.)
----The above is just A small randomized controlled trial reported that compression stockings reduced the start. The flattening index is a rather complex calculation taking many factor number of apneas and hypopnea, perhaps by "prevention of fluid accumulation in the legs during the day, and its nocturnal displacement into considerationthe neck at night. Do read the entire patent application if you really want to get your head spinning,"
----'''Oropharyngeal muscle exercises'''
===Leak Rate===One study showed that playing the [[didgeridoo]] may reduce snoring and daytime sleepiness due to OSA. Since OSA is sometimes caused by hypotonicity (low tone) in the muscles of the throat, playing the didgeridoo may improve symptoms of sleep apnea by exercising muscles of the throat and increasing tone.
The leak rate graph indicates whether excessive mask leaking occurred, and A study published in 2009 tested the effect of a set of oropharyngeal exercises developed from exercises used by speech-language pathologists to what extentimprove swallowing function. All CPAP masks are designed to leak or vent surplus air away from Participants with moderate OSA who performed the user's nose or mouth. This flushes away the exhaled breath exercises every day showed a significant decrease in snoring frequency, snoring intensity, daytime sleepiness, sleep quality score, neck circumference, and prevents the user from re-breathing his expelled CO2AHI score when compared with a control group who performed sham exercises. The actual amount of improvement in OSA shown by this designed leak will vary according group was comparable to the mask. Anything improvement shown in excess of that amount is an "additional leak"patients who use oral appliances to treat this condition.
Resmed machines show Although this study was not designed to determine which specific exercises were beneficial, an editorial response to this study in the same journal argues that only 2 of the set of exercises were likely capable of effecting the improvements they reported. These 2 exercises included sucking the tongue upward against the palate for a single trace indicating total of 3 minutes throughout the additional leak. By default (day, and inflating a balloon by blowing forcefully and then breathing in accordance with Resmed guidelines)deeply through the nose, Oscar flags any additional leak over 24 L/min as an excessive or "large leak"repeated 5 times without removing the balloon from the mouth. You can adjust The tongue exercise is intended to increase the red line between acceptable strength of tongue protrusion, and unacceptable leaks by using '''File | Preferences | CPAP | Flag leaks over threshold'''the balloon exercise is intended to increase the strength of the pharyngeal wall. Although more research is needed to clarify the effects of oropharyngeal exercise on OSA, this recent study suggests a promising new approach to treating the condition.
Philips machines show two traces - total leak and additional leak. It is the lower additional leak line that indicates whether the leak is excessive or not.'''Positional treatments'''
Many people benefit from sleeping at a 30 degree elevation of the upper body or higher, as if in a recliner. Doing so helps prevent the gravitational collapse of the airway. Lateral positions (sleeping on a side), as opposed to [[File:OSCAR Leak graph Resmed.png | 1200 px | Leak graph from Resmed machine showing excessive leakagesupine position]]<br>'''Leak graph from Resmed machine showing excessive leakage'''s (sleeping on the back), are also recommended as a treatment for sleep apnea, largely because the gravitational component is smaller than in the lateral position. A 30 degree elevation of the upper body can be achieved by sleeping in a recliner, an adjustable bed, or a bed wedge placed under the mattress. This approach can easily be used in combination with other treatments and may be particularly effective in very obese people.
<br>[[File:OSCAR Leak graph Philips.png | 1200 px | Leak graph from Philips machine showing upper and lower traces]]<br>'''Leak graph from Philips machine showing upper and lower traces'''<br>== Prognosis ==
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===Snore===
Resmed and Philips machines both show snoring as Many studies indicate that it is the effect of a graph "fight or flight" response on the body that happens with each apneic event that increases health risks and consequences in OSA. The fight or flight response causes many hormonal changes in the height of body; those changes, coupled with the trace indicating the intensity low oxygen saturation level of the snoring. In additionblood, Philips machines show individual snores as events labeled VS1 and VS2 (vibratory snore 1 and 2). It is usually suggested that VS2 be turned off when presenting screenshots for discussion as the large number of events recorded can overwhelm other data on cause damage to the charts. <br><br>[[File:OSCAR Snorebody over time.png | 1200 px | OSCAR snore graph from Resmed machine ]]<br>'''OSCAR snore graph from Resmed machine '''
Snores can be precursors Although it takes some trial and error, most patients find a combination of obstructive treatments which reduce apnea events and improve their overall health, energy, and well-being. Without treatment, the [[sleep deprivation]] and lack of oxygen caused by sleep apnea increases health risks such as such drive cardiovascular disease, high blood pressure increases, especially with Phillips Respironics machinesstroke, diabetes, clinical depression, weight gain and obesity.
The most serious consequence of untreated OSA is to the heart. Sleep apnea sufferers have a 30% higher risk of heart attack or death than those unaffected. In severe and prolonged cases, there are increases in pulmonary pressures that are transmitted to the right side of the heart. This can result in a severe form of congestive heart failure known as cor pulmonale. One prospective study showed that patients with OSA, compared with healthy controls, initially had statistically significant increases in vascular endothelial growth factor (P=.003) and significantly lower levels of nitrite-nitrate (P=.008), which might be pathogenic factors in the cardiovascular complications of OSA. These factors reversed to normal levels after 12 weeks of treatment by CPAP, but further long---term trials are needed to assess the impact of this therapy.
===Zeo Data===If data has been imported from Elevated arterial pressure (i.e., hypertension) can be a Zeo sleep monitor deviceconsequence of OSA syndrome. When hypertension is caused by OSA, additional graphs will be availableit is distinctive in that, including Sleep stageunlike most cases (so-called essential hypertension), the readings do not drop significantly when the individual is sleeping. Stroke is also known to be associated with OSA.
[[File:OSCAR Zeo.png | 800 px]]
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==Daily (Advanced Charts)==
To reset the graph order for the Advanced Charts click on '''''View/Reset Graphs/Advanced'''''<br>
===Event Flags===see Daily (Standard Charts)above for discussion.---- ===Flow Rate===see Daily (Standard Charts)above for discussion.====Why Pressure Support (PS/EPR)====''For our purposes, Pressure Support and EPR may be considered the same, with that provided by a BiLevel having the capability of a much higher value and can be applied in smaller increments.''<br /> The way we know that more pressure support (difference between inhale and exhale pressure) is needed is that there is a relatively long inspiration time compared to expiration time. This happens when a person has considerable airway resistance or obstruction which requires more work and more time to get the volume of air needed to satisfy respiratory needs. Pressure support from bilevel therapy can actually off-load some of the physical effort of inspiration to the machine and help you fill your lungs easier and more rapidly. The increase in ventilation can reduce your CO2 level which affects respiratory drive. This is what causes some of the CA events. (looking for chart to demonstrate this)---- ===Mask Pressure=== Mask Pressure is used in advanced cases such as for Central Apnea or other breathing issues where the breathing is paced (Timed) such as in some cases of COPD. It lets us see how the pressure is being delivered. ====ResMed ASV - Example==== See the relationship between Pressure and Mask Pressure. The Pressure chart looks a little jointed, because of its resolution. I view it as the current target pressure. Here there are two plots, the top red one is IPAP or inhale pressure, the bottom green one is EPAP or Exhale pressure, the difference is the intended Pressure Support (or EPR with an AirSense)<br>Mask Pressure is the Pressure at the mask. It is recorded in much higher resolution than Pressure is.   In this example, you can see the shape of the pressure delivered by the Resmed ASV. Compare it to the square-wave which is what Philips gives, even with Flex at 3. Look how normal the resulting respiratory flow rate is. Midway through this graph is an obstructive UA event (we know it's obstructive because the Resmed doesn't miss a central). Note how quickly pressure hits the top of the PS setting when a breath is missed. It doesn't step up over 4-breaths, it comes in right away and backs off as soon as respiration is spontaneous. The Philips lags in both directions. As a result, the Resmed does not very often miss its minute vent target. [[FileCategory:ASV Mask Pressure - ResMed.png|800px]] ----===Tidal Volume=== Tidal volume is the amount of air that moves in or out of the lungs with each respiratory cycle. It measures around 500 mL in an average healthy adult male and approximately 400 mL in a healthy female. It is a vital clinical parameter that allows for proper ventilation to take place. When a person breathes in, oxygen from the surrounding atmosphere enters the lungs. It then diffuses across the alveolar-capillary interface to reach arterial blood. At the same time, carbon dioxide continuously forms as long as metabolism takes place. Expiration occurs to expel carbon dioxide and prevent it from accumulating in the body. The volume of inspired and expired air that helps keep oxygen and carbon dioxide levels stable in the blood is what physiology refers to as tidal volume. The normal tidal volume is 6 to 8 ml/kg. Normal results typically range between 80% and 120% of the prediction. Traditional preset tidal volumes higher than 10 ml/kg have been proved to be associated with increased risk of pulmonary barotrauma and should be avoided. High tidal volumes also decrease venous return and reduce cardiac output. ====Calculating Tidal Volume Range====female, IBW = 45.5 + (2.3 * (height [in] - 60)); andmale, IBW = 50 + (2.3 * (height [in] - 60)), Minimal Tidal Volume = 6 ml/kg * IBW Maximal Tidal Volume = 8 ml/kg * IBW. ====Tidal Volume During Sleep==== Sleep alters respiratory physiology in various ways. REM sleep, in particular, is the sleep phase with the highest degree of breathing irregularity, both in frequency and respiratory rate. During REM, almost all body muscles, including respiratory muscles, become hypotonic, except for the diaphragm. Therefore, a person relies on the diaphragm to maintain an adequate tidal volume during REM. Additionally, respiratory response to hypoxic and hypercapnic stimuli decreases, not to mention the decreased central respiratory drive, which, along with accessory muscle paralysis, leads to a slight decrease in tidal volume and minute ventilation. The change is usually not prominent in healthy individuals but becomes prominent in patients with preexisting respiratory disease.  ====ASV====Tidal Volume is managed by Philips Respironics ASV for the purpose of managing Central Sleep Apnea. ResMed ASV maintains a constant Minute Volume to manage Central Sleep Apnea. ====Clinical Significance====I've included these because it is important to understand the potential impact of these Clinical diseases with an xPAP machine. =====Restrictive Lung Diseases===== Restrictive lung diseases are a group of chronic pulmonary conditions characterized by the inability of the lungs to fully expand, owing to problems in the lungs themselves or the structures surrounding them. Interstitial lung diseases, such as idiopathic pulmonary fibrosis and asbestosis, cause progressive fibrosis of the lung tissue. As such, they represent an intrinsic lung pathology that leads to a restrive physiology due to increased stiffness and decreased compliance. Morbid obesity and sarcoidosis are examples of extrinsic problems that cause restriction by limiting chest wall expansion. In restrictive lung disease, the patient adapts a breathing pattern of rapid, shallow breaths to minimize the work of breathing. =====Obstructive Lung Diseases===== The hallmark of obstructive lung disease is difficulty expelling air out of the lungs due to progressive airway narrowing. Chronic obstructive pulmonary disease (COPD) and asthma are the two typical examples of obstructive lung disease. Asthma is a reversible condition characterized by airway hyperresponsiveness to various stimuli. It causes episodes of excessive mucous production, bronchoconstriction, and airway narrowing. On the other hand, COPD is an irreversible chronic inflammatory process that leads to a gradual reduction in the lumen of the conducting airways. As the condition progresses, air-trapping ensues, leading to lung hyperinflation. Since the problem in obstructive lung disease is expiratory, breathing with higher tidal volumes helps overcome airway resistance. Therefore, patients acquire a breathing pattern of deep, slow breaths to minimize the work of breathing. =====Mechanical Ventilation===== Acute respiratory distress syndrome, or ARDS, is a condition characterized by widespread inflammation of the lungs following an inciting pulmonary or extrapulmonary event. ARDS usually causes hypoxemic respiratory failure or critically low arterial oxygen tension necessitating mechanical ventilation. Patients with ARDS already have injured lungs, and mechanical ventilation should follow a lung-protective strategy. In other Medical terms, tidal volumes should be kept as low as possible to prevent volutrauma and barotrauma. The problem in ARDS is that pulmonary edema and distal airway collapse decrease the surface area of the aerated lungs. Therefore, ventilation with large or even regular tidal volumes may cause hyperinflation of the healthy aerated portion of the lungs since air does not reach the already collapsed airways. As a result, alveolar overdistension and lung injury might occur. Generally, lung-protective strategies in patients with ARDS involve administering tidal volumes of approximately 6-8 mL/Kg of ideal body weight.[8][9] =====Neuromuscular Disease===== Neuromuscular diseases refer to a group of disorders characterized by progressive muscle weakness due to problems in the muscles themselves or the nerves that supply them. Patients with neuromuscular diseases (NMDs) eventually develop respiratory muscle weakness. The diaphragm is the primary muscle of inspiration and is the one most commonly affected in NMDs. Patients with a weak diaphragm rely on other muscles of inspiration, such as the external intercostals, to maintain adequate tidal volume. During REM sleep, there is generalized hypotonia of all respiratory muscles, except for the diaphragm, and a healthy person becomes diaphragm dependent. In patients with NMDs, dyspnea becomes prominent at night due to diaphragmatic weakness. Nocturnal REM-related hypoventilation is one of the earliest signs of respiratory muscle involvement in neuromuscular disease. As the disease progresses, daytime symptoms become prominent, and patients rely on a breathing pattern similar to the one seen in other restrictive lung diseases, i.e., shallow, rapid breathing.[10][11] [https://www.ncbi.nlm.nih.gov/books/NBK482502/#:~:text=Tidal%20volume%20is%20the%20amount,proper%20ventilation%20to%20take%20place. Physiology, Tidal Volume] ----  ===Minute Vent===Minute ventilation, also known as total ventilation, is a measurement of the amount of air that enters the lungs per minute. It is the product of respiratory rate and tidal volume. Minute ventilation (or respiratory minute volume or minute volume) is the volume of gas inhaled (inhaled minute volume) or exhaled (exhaled minute volume) from a person's lungs per minute. It is an important parameter in respiratory medicine due to its relationship with blood carbon dioxide levels. Normal minute ventilation is between 5 and 8 L per minute (Lpm). Tidal volumes of 500 to 600 mL at 12–14 breaths per minute yield minute ventilations between 6.0 and 8.4 L, for example. Minute ventilation can double with light exercise, and it can exceed 40 Lpm with heavy exercise.  ====ASV====ResMed ASV maintains a constant Minute Volume to manage Central Sleep Apnea. Philips Respironics ASV manages Tidal Volume for the purpose of managing Central Sleep Apnea.  ---- ===Insp. Time======Exp. Time======Resp. Rate=== ----==Daily (Other Charts)=====AHI=== This chart is basically a running count of the number of 'events' (OA + CA + H) in the previous 60 minutes. As such, it is not particularly useful, since you can see the clusters in the Event Flags chart at the top, and also see which types of events are occurring. The y-value of the OSCAR AHI graph at any given time is the total number of events recorded during the previous 60 minutes of run time in the current session. When a particular event becomes one hour old, it is dropped from the running total. The following image shows a series of 3 events scored within an 8-minute period, followed by over an hour of sleep where no additional OA, CA, or H events were scored. The AHI first increases to 3 and it stays at 3 until each of the three events "age" out of the running total:<br /> [[File:ahi-graph-balanced_zpsa8d453f9.jpg]] ---- ===Time at Pressure=== The ''Time at Pressure'' graphs the amount of time spent at a specific pressure. The ''Time at Pressure'' is a companion graph of the ''Pressure'' graph, using the same data and configuration.<br />The ''Time at Pressure'' has pressure on the x-axis and time duration (in minutes) on the y-axis. The following picture is from a CPAP device where the pressure is at a constant eight(8) cmH2O. <br />The picture contains the OSCAR charts: Event Flags, Pressure, and Time at Pressure. [[FileCategory:TimeAtPressure_CPAP_example.png|thumb|center|1000px|Time at pressure CPAP deviceConditions]]<br /> The following picture is from a APAP device where there were two events that occured at Pressure Interval 8.6 cmH2O (8.5<= P < 8.7). A CA (Clear Airway) and a OA (Obstructive) apneas occured during this pressure interval. <br />These two event are indicated by dashed lines and circles.<br />The Pressure Interval for 8.6 is highlighted in yellow. [[FileCategory:TimeAtPressure_APAP_example.png|thumb|center|1000px|Time at pressure APAP deviceDiagnosis]]<br /> A mouse-over event over the ''Time at Pressure'' chart will accentuate the data points.<br />A mouse-over event for a pressure interval will accentuate its data point in black. Both ''Events'' and ''SPAN Events'' are supported similar to the Pressure Graph.Multiple plots for IPAP and EPAP are also supported.<br />The Pressure graph's configuration menus for '''Plots''' and '''CPAP Overlays''' are used to configure the Time at Pressure graphs. [[File:TimeAtPressure_OVERLAY_example.png|thumb|center|1000px|Time at pressure APAP device]]<br /> ---- =CPAP Algorithims=[[CPAP Algorithms]]To assist in understanding your devices responses =OSCAR Calculations=This section is new and under development, so please bear with us.<br>Mostly OSCAR is a reporter, it is even in the name, '''OSCAR''' - the '''O'''pen '''S'''ource '''C'''PAP '''A'''nalysis '''R'''eporter.<br />  Here is what OSCAR calculates, including the math behind it.<br> ----==Insp. Time==*Some ResMed's do not report I and E times, Which ones do not (AutoSet, Elite?). Which ones are "Calculated" by OSCAR? ----==Exp. Time==*Some ResMed's do not report I and E times, Which ones do not (AutoSet, Elite?). Which ones are "Calculated" by OSCAR?----==Compliance==There are several different Compliance requirements out there, FAA, DOT, Medical Insurance. These requirements vary by the requiring organization and may even vary by country. It is the certifying organization that determines what the criteria is and it is they who may or may not accept OSCAR data as satisfying their documentation requirements. <br>The compliance requirements vary by the number of days use over a period of time and the required number of hours use per day. If the xPAP is not used during any given day it is considered a "non-compliant" day.*Compliance is calculated by OSCAR. ---- ==Respiration Rate, Tidal Volume, and Minute Vent=====ResMed===ResMed machines record Respiration Rate, Tidal Volume, and Minute Vent, they are not calculated. ===SleepStyle CPAP===SleepStyle CPAP does not record these so OSCAR calculates those numbers from the flow graph. ===DeVilbiss===DeVilbiss is in between with Respiration Rate and Tidal Volume being reported with Minute Vent calculated as the product of Respiration Rate and Tidal Volume. ----
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